Related Experiment Video
Updated: Apr 27, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
Published on: January 16, 2016
Maze solving using fatty acid chemistry
Kohta Suzuno1, Daishin Ueyama, Michal Branicki
1Graduate School of Advanced Mathematical Sciences, Meiji University , Tokyo, Japan.
Abstract:
This study demonstrates that the Marangoni flow in a channel network can solve maze problems such as exploring and visualizing the shortest path and finding all possible solutions in a parallel fashion. The Marangoni flow is generated by the pH gradient in a maze filled with an alkaline solution of a fatty acid by introducing a hydrogel block soaked with an acid at the exit. The pH gradient changes the protonation rate of fatty acid molecules, which translates into the surface tension gradient at the liquid-air interface through the maze. Fluid flow maintained by the surface tension gradient (Marangoni flow) can drag water-soluble dye particles toward low pH (exit) at the liquid-air interface. Dye particles placed at the entrance of the maze dissolve during this motion, thus exhibiting and finding the shortest path and all possible paths in a maze.
Related Concept Videos
Overview of Fatty Acid Metabolism
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Mechanism
Lipids as Anchors
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Overview
Membrane Fluidity
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
Membrane Fluidity

