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Related Concept Videos

Esophageal Achalasia01:27

Esophageal Achalasia

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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide...
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Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
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Gastroesophageal Reflux Disease01:25

Gastroesophageal Reflux Disease

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Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
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Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

841
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
841
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

2.4K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

2.0K
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
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Related Experiment Video

Updated: Apr 27, 2026

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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Recurrent spontaneous esophageal dissection.

Nicholas A Stephens1, Shinil K Shah2, Peter A Walker1

  • 1Department of Surgery, University of Texas Medical School at Houston, Houston, TX, USA.

JSLS : Journal of the Society of Laparoendoscopic Surgeons
|June 25, 2014
PubMed
Summary
This summary is machine-generated.

Recurrent spontaneous esophageal dissection, though rare, can be managed with endoscopic therapy. This case highlights successful treatment in a patient with chronic eosinophilic esophagitis, preventing further episodes.

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Area of Science:

  • Gastroenterology
  • Esophageal Disorders
  • Medical Case Studies

Background:

  • Spontaneous esophageal dissection (SED) is a rare condition.
  • Chronic eosinophilic esophagitis (CEE) is an allergic inflammatory disease of the esophagus.

Observation:

  • A 33-year-old man with CEE experienced two episodes of spontaneous esophageal dissection within 5 months.
  • Both dissection episodes occurred in the mid-esophagus.

Findings:

  • The patient's recurrent esophageal dissection was successfully treated with endoscopic intervention.
  • Definitive endoscopic therapy and oral steroids prevented further recurrences.

Implications:

  • Endoscopic therapy is a viable management option for recurrent spontaneous esophageal dissection.
  • This case suggests a potential link between CEE and SED, warranting further investigation.