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Eosinophilic mastitis masquerading as breast carcinoma.
Journal of Surgical Case Reports
|June 25, 2014
Summary
Eosinophilic mastitis, a rare breast condition, can mimic breast cancer. Early diagnosis through open biopsy is crucial, especially in asthmatic patients with peripheral eosinophilia, to avoid unnecessary surgery.
Area of Science:
- Oncology
- Pathology
- Immunology
Background:
- Eosinophilic mastitis is a rare breast condition.
- It can present with symptoms mimicking breast carcinoma, leading to diagnostic challenges.
- It is associated with peripheral eosinophilia and can be linked to asthma and hyper-eosinophilic syndromes.
Purpose of the Study:
- To report the sixth case of Eosinophilic Mastitis.
- To highlight its presentation mimicking breast carcinoma.
- To emphasize the importance of considering this diagnosis in specific patient profiles.
Main Methods:
- Case report of a 50-year-old female patient.
- Clinical examination, mammography, and axillary lymphadenopathy assessment.
- Needle cytology, Tru-cut biopsy, peripheral blood investigations, and open biopsy for diagnosis.
Main Results:
- Initial investigations suggested malignant disease.
- Cytology and Tru-cut biopsy were inconclusive or showed inflammation.
- Open biopsy confirmed Eosinophilic Mastitis, correlating with peripheral eosinophilia and pulmonary symptoms.
- The patient responded to conservative management.
Conclusions:
- Eosinophilic mastitis is a rare manifestation of tissue eosinophilia.
- It can be misdiagnosed as breast cancer due to similar clinical and radiological features.
- Considering eosinophilic mastitis in asthmatic patients with peripheral eosinophilia and inconclusive breast lump investigations can prevent unnecessary surgical intervention.
