Related Experiment Video
Updated: Apr 27, 2026

10:58
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
10.4K
Quinary debulking for epithelial ovarian cancer
James M Edwards1, William Jeffrey Lowery1, Angeles Alvarez Secord1
1Duke University Medical Center, Durham, USA.
Journal of Surgical Case Reports
|June 25, 2014
Summary
Optimal quinary debulking surgery successfully treated recurrent ovarian cancer that spread to the liver, diaphragm, and lung. This extensive procedure was well-tolerated, with no residual disease found 6 months post-surgery.
Area of Science:
- Oncology
- Surgical Oncology
- Gynecologic Oncology
Background:
- Recurrent papillary serous carcinoma of the ovary can involve extensive upper abdominal and thoracic structures.
- Multiple debulking procedures for advanced ovarian cancer remain controversial due to complexity and potential morbidity.
Purpose of the Study:
- To report a case of successful extensive surgical debulking for recurrent ovarian cancer with diaphragmatic and pulmonary involvement.
- To highlight selection criteria for patients undergoing such aggressive surgical interventions.
Main Methods:
- The patient underwent optimal quinary debulking surgery.
- Surgical extent included resection of ovarian cancer involving the liver parenchyma, diaphragm, and lung parenchyma.
Main Results:
- The patient tolerated the extensive surgical procedure well.
- No evidence of residual disease was observed at 6 months postoperatively.
Conclusions:
- Optimal quinary debulking can be a viable option for selected patients with recurrent ovarian cancer involving thoracic structures.
- Careful patient selection based on functional status, disease-free interval, and absence of systemic disease is crucial for favorable outcomes.

