Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Papillary Dermis01:11

Papillary Dermis

5.8K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.8K
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

3.7K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
3.7K
Reticular Dermis01:15

Reticular Dermis

4.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
4.6K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SiO<sub>2</sub>@antisense molecules covered by nepetalactone, extracted from Nepeta gloeocephala, inhibits ILK phosphorylation and downstream PKB/AKT signaling in HeLa cells.

Cancer gene therapy·2016
Same author

Running barbed suture quilting reduces abdominal drainage in perforator-based breast reconstruction.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2015
Same author

Knowledge of plastic surgery trainees on the management of traumatic dental and facial bone injuries.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2015
Same author

Finger tourniquets: two safe and cost effective techniques and a discussion of the literature.

Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·2013
Same author

Reversal of hand peripheral ischaemia due to extravasation of adrenaline during cardiopulmonary resuscitation.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2013
Same author

Radiographic signs of static carpal instability with distal end radius fractures: is current treatment adequate?

Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·2012

Related Experiment Video

Updated: Apr 27, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

18.1K

Dermatofibrosarcoma protuberans: A rare cutaneous tumour.

R Van Der Rijt1, P Moradi1

  • 1Prince of Wales Hospital, Sydney, Australia.

Journal of Surgical Case Reports
|June 25, 2014
PubMed
Summary

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor. This case highlights the challenges of facial DFSP and proposes a treatment algorithm for head and neck region cases.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Head and Neck Surgery

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue neoplasm.
  • DFSP is characterized by local aggressiveness and a high rate of recurrence.
  • Facial DFSP presents unique oncological, functional, and aesthetic challenges due to the region's complexity.

Purpose of the Study:

  • To present a rare case of DFSP in the head and neck region.
  • To discuss the management challenges associated with facial DFSP.
  • To review literature and propose a treatment algorithm for head and neck DFSP.

Main Methods:

  • Case presentation of a young gentleman with facial DFSP.
  • Comprehensive literature review focusing on head and neck DFSP.

More Related Videos

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

3.1K
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.8K

Related Experiment Videos

Last Updated: Apr 27, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

18.1K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

3.1K
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.8K
  • Development of a treatment algorithm based on evidence.
  • Main Results:

    • The case illustrated significant oncological, functional, and aesthetic considerations.
    • Literature review identified specific challenges and treatment modalities for head and neck DFSP.
    • A novel treatment algorithm was devised for managing DFSP in this region.

    Conclusions:

    • Facial DFSP requires a multidisciplinary approach for optimal outcomes.
    • The proposed treatment algorithm provides evidence-based guidance for head and neck DFSP management.
    • Further research is warranted to refine treatment strategies for rare soft tissue tumors.