Proctocolectomy for persistent haematochezia in a patient with Cronkhite-Canada Syndrome

N Wijekoon1, M Samarasinghe1, U Dalpatadu1

  • 1University of Colombo, Sri Lanka.

Insights

Cronkhite-Canada syndrome, a rare gastrointestinal polyposis, presents with diarrhea and taste changes. This case highlights surgical management for severe bleeding, leading to a full recovery.

Area of Science:

  • Gastroenterology
  • Gastrointestinal Pathology
  • Medical Case Reports

Background:

  • Cronkhite-Canada syndrome (CCS) is an exceptionally rare disorder characterized by diffuse gastrointestinal polyposis.
  • Key features include diarrhea, dysgeusia (altered taste), and ectodermal abnormalities.
  • Polyps typically affect the entire GI tract, excluding the esophagus.

Purpose of the Study:

  • To report a unique case of Cronkhite-Canada syndrome presenting with severe, recurrent hematochezia.
  • To illustrate the diagnostic process and management of medically refractory bleeding in CCS.
  • To highlight the successful surgical outcome in a patient with severe gastrointestinal manifestations of CCS.

Main Methods:

  • A comprehensive literature review was performed.
  • Clinical presentation, diagnostic investigations, and treatment of a 50-year-old male patient with CCS were detailed.
  • The patient underwent proctocolectomy for intractable hematochezia.

Main Results:

  • The patient presented with recurrent severe hematochezia due to colonic polyps.
  • Diagnosis of Cronkhite-Canada syndrome was confirmed.
  • Proctocolectomy resulted in complete resolution of symptoms, with the patient remaining asymptomatic.

Conclusions:

  • Cronkhite-Canada syndrome requires careful diagnosis and management, especially when presenting with severe gastrointestinal bleeding.
  • Surgical intervention, such as proctocolectomy, can be an effective option for refractory cases.
  • This case underscores the importance of considering rare conditions in patients with complex gastrointestinal symptoms.

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