Post-traumatic pelvic extramedullary haemopoetic tissue causing lower urinary tract symptoms

Area of Science:

• Hematology
• Urology
• Pathology

Background:

• Extramedullary haemopoiesis (EMH) is hematopoietic tissue development outside the bone marrow.
• EMH is typically asymptomatic and associated with myelodysplastic syndromes.
• Trauma is not a commonly recognized cause of EMH.

Purpose of the Study:

• To report the first case of post-traumatic extramedullary haemopoiesis.
• To describe the unusual presentation of EMH with lower urinary tract symptoms.
• To highlight the diagnostic considerations for EMH in trauma patients.

Main Methods:

• Case report.
• Clinical presentation review.
• Literature review for similar cases.

Main Results:

• The patient presented with lower urinary tract symptoms.
• Imaging and biopsy confirmed extramedullary haemopoiesis.
• The EMH was attributed to a prior traumatic injury.

Conclusions:

• Post-traumatic EMH can manifest with lower urinary tract symptoms.
• EMH should be considered in the differential diagnosis of urinary symptoms following trauma.
• This case expands the known clinical spectrum of extramedullary haemopoiesis.