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Related Concept Videos

Appendicitis01:19

Appendicitis

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Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
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Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
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Polymicrobial abdominal wall necrotizing fasciitis after cesarean section.

Jp DeMuro1, Af Hanna1, E Chalas1

  • 1Winthrop University Hospital, Mineola, New York, USA.

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|June 25, 2014
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Summary

A woman developed severe necrotizing fasciitis after a cesarean section and non-steroidal anti-inflammatory drug (NSAID) use. This case highlights the potential increased risk of this serious infection associated with NSAIDs.

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Area of Science:

  • Infectious Diseases
  • Surgery
  • Pharmacology

Background:

  • Necrotizing fasciitis is a severe soft tissue infection.
  • Postpartum complications can include serious infections.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.

Purpose of the Study:

  • To report a rare case of polymicrobial necrotizing fasciitis following a cesarean section.
  • To investigate the potential association between NSAID use and the development of necrotizing fasciitis.
  • To highlight the diverse microbial agents involved in postpartum necrotizing fasciitis.

Main Methods:

  • Case report detailing a patient's clinical presentation and treatment.
  • Review of medical history, including medication use (NSAID) and surgical procedures (cesarean section).
  • Microbiological analysis to identify causative organisms of the polymicrobial infection.

Main Results:

  • A previously healthy woman developed polymicrobial necrotizing fasciitis post-cesarean section.
  • The patient received a non-steroidal anti-inflammatory drug (NSAID) postpartum.
  • Infection led to septic shock, requiring extensive debridement and abdominal reconstruction.
  • Causative organisms included Staphylococcus aureus, Enterobacter agglomerans, Acinetobacter baumannii, and Enterobacter cloacae.

Conclusions:

  • NSAID use may be associated with an increased risk of necrotizing fasciitis in the postpartum period.
  • Polymicrobial infections involving unusual organisms can complicate postpartum recovery.
  • Prompt diagnosis and surgical intervention are critical for managing necrotizing fasciitis.