Related Experiment Video
Updated: Apr 27, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
[Unusual cause of orbital mass]
A Rübsam1, K Erb-Eigner, P Lohneis
1Klinik für Augenheilkunde, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Deutschland, anne.ruebsam@charite.de.
Case Report:
A 54-year-old female presented with a progressive swelling of the upper eyelid since 6 months. Magnetic resonance imaging (MRI) showed an extraconal supratemporal orbital lesion. After resection the histopathological diagnosis confirmed a Merkel cell carcinoma in the lacrimal gland.
Clinical Course:
Due to an incomplete resection the patient underwent adjuvant radiochemotherapy and is relapse-free for 1.5 years.
Conclusion:
Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor, usually occurring on sun-exposed skin and in 10% in the region of the eyelids. The occurrence of MCC in the lacrimal gland is even less common with only two published cases.
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