Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Couples Therapy01:26

Couples Therapy

468
Couples therapy is a therapeutic approach designed to help individuals in intimate relationships address conflicts, improve communication, and foster healthier dynamics. It is appropriate for couples at various stages, including those who are dating, married, or in long-term partnerships, and aims to support partners in navigating their unique relational challenges.
Core Principles and Techniques
Couples therapy often incorporates cognitive-behavioral principles to identify and modify negative...
468
Relationship Formation02:12

Relationship Formation

28.4K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
28.4K
Nurses' Legal Responsibilities II01:23

Nurses' Legal Responsibilities II

1.9K
Establishing a secure, collaborative nurse-patient relationship is crucial for delivering high-quality care. This relationship, founded on trust, respect, and honesty, enhances the patient's comfort and willingness to share vital health information. For example, a nurse who listens actively and without judgment provides clear information about health conditions and treatment options and respects patient decisions, which builds a trusting relationship.
Communication between nurses and...
1.9K
Nurses' Legal Responsibilities III01:16

Nurses' Legal Responsibilities III

1.9K
Nurse-to-nurse relationships are legally required to adhere to professional standards, ensuring a respectful and positive working environment. Professional conduct demands that nurses treat all colleagues respectfully and courteously, fostering a productive, supportive workplace. Nurses must actively eliminate bullying, discrimination, and harassment to maintain a safe and inclusive environment.
Cultivating a culture of collaboration and mutual respect among nurses transcends mere enhancement...
1.9K
National Nursing Organizations II01:30

National Nursing Organizations II

2.0K
Nursing organizations play a vital role in representing nurses working in specialized clinical settings, such as the American Association of Critical-Care Nurses (AACN).
The AACN emphasizes a healthy work environment through six standards to achieve an optimal patient outcome. The standards are appropriate staffing, meaningful recognition, collaboration, authentic leadership, effective communication, and decision-making. In addition, AACN provides certification programs, webinars, journals, and...
2.0K
Interdisciplinary Care: The Health Care Team-II01:18

Interdisciplinary Care: The Health Care Team-II

2.2K
An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care. Here are a few more healthcare professionals.
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The adiponectin agonist AdipoRon accelerates osteoporosis development in two different models and modulates adipocyte differentiation.

Bone·2025
Same author

Behavior as additional endpoint for effect assessment of diazinon in Daphnia magna.

Ecotoxicology and environmental safety·2025
Same author

Exploration of circulating metabolites in infants with abusive head trauma.

Current research in neurobiology·2025
Same author

Integrated GWAS and metabolomic analyses identified metabolic pathways and candidate genes involved in free asparagine accumulation in durum wheat grain.

Food chemistry·2025
Same author

A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse model.

European journal of medicinal chemistry·2025
Same author

Activity-Based Proteome Profiling of Serum Serine Hydrolases: Application in Pediatric Abusive Head Trauma.

Proteomics. Clinical applications·2024
Same journal

Future Directions in Biotechnological and Pharmacological Applications of CAIs.

Sub-cellular biochemistry·2026
Same journal

Industrial and Environmental Applications of Carbonic Anhydrases.

Sub-cellular biochemistry·2026
Same journal

Applications of Carbonic Anhydrase Inhibitors in Arthritis, Neuropathic Pain, Acute Mountain Sickness, and Cerebral Ischemia.

Sub-cellular biochemistry·2026
Same journal

Applications of Carbonic Anhydrase Inhibitors in Neurological Disorders, Mechanisms and Therapeutic Potential.

Sub-cellular biochemistry·2026
Same journal

Carbonic Anhydrase Inhibitors in Oncology.

Sub-cellular biochemistry·2026
Same journal

Therapeutic Applications of Carbonic Anhydrase Inhibitors in Ophthalmology.

Sub-cellular biochemistry·2026
See all related articles

Related Experiment Video

Updated: Apr 27, 2026

Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.2K

RXRs: collegial partners.

Federica Gilardi1, Béatrice Desvergne

  • 1Center for Integrative Genomics, University of Lausanne, Genopode Building, 1015, Lausanne, Switzerland, Federica.Gilardi@unil.ch.

Sub-Cellular Biochemistry
|June 26, 2014
PubMed
Summary
This summary is machine-generated.

Retinoid X Receptors (RXRs) are crucial nuclear receptors that form partnerships with other receptors. Understanding their genome-wide activity is key to exploring RXRs as potential therapeutic targets.

More Related Videos

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

26.2K
The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm
06:18

The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm

Published on: October 20, 2022

2.3K

Related Experiment Videos

Last Updated: Apr 27, 2026

Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.2K
Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

26.2K
The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm
06:18

The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm

Published on: October 20, 2022

2.3K

Area of Science:

  • Molecular Biology
  • Genetics
  • Endocrinology

Background:

  • Retinoid X Receptors (RXRs) bind 9-cis retinoic acid, but their endogenous activator remains unclear.
  • RXRs are essential partners for other nuclear receptors, integrating diverse signaling pathways.
  • RXRs play a pivotal role in the nuclear receptor superfamily.

Purpose of the Study:

  • To describe the structural basis of RXR homo- and heterodimerization.
  • To elucidate the functional consequences of RXR dimerization.
  • To highlight the importance of genome-wide RXR activity studies for therapeutic target identification.

Main Methods:

  • Structural analysis of RXR dimerization.
  • Functional assays for RXR activity.
  • Genome-wide studies of RXR-mediated gene regulation.

Main Results:

  • Detailed structural insights into RXR homo- and heterodimer formation.
  • Functional characterization of RXR dimerization's impact on signaling pathways.
  • Identification of genome-wide targets and biological roles of RXRs.

Conclusions:

  • RXR dimerization is a key structural and functional feature.
  • Genome-wide analysis is crucial for understanding RXR's biological significance.
  • RXRs represent promising targets for novel therapeutic strategies.