Recent advances in the synthesis of nitroolefin compounds
Guobing Yan1, Arun Jyoti Borah, Lianggui Wang
1Department of Chemistry, Lishui University, No. 1, Xueyuan Road, Lishui City 323000, Zhejiang Province, P. R. China. 0gbyan@tongji.edu.cn.
Abstract:
Development of methodology for the preparation of nitroolefins is of significant interest to organic chemists. Recently, numerous useful methods have been developed, mainly including direct nitration of olefinic C-H bonds, nitro-decarboxylation of aromatic α,β-unsaturated carboxylic acids, ipso-nitration of vinylboronic acids and multidehydrogenative cross-coupling reaction of (hetero)arenes with nitroethane. This review will focus on recent achievements in nitroolefin synthesis and the mechanisms of the reactions are also discussed.
Related Concept Videos
Nitrosation of Enols
Preparation of Amines: Reduction of Oximes and Nitro Compounds
Though catalytic hydrogenation can reduce nitrobenzenes, the reduction is nonselective in the presence of other functional groups. For instance, if nitrobenzene contains an aldehyde group,...
Preparation of Nitriles
Olefin Metathesis Polymerization: Overview
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Synthesis of α-Substituted Carbonyl Compounds: The Stork Enamine Reaction
Electrophilic Aromatic Substitution: Nitration of Benzene

![Solid-phase Synthesis of [4.4] Spirocyclic Oximes](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58508.jpg&w=3840&q=50)
