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Updated: Apr 27, 2026

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
[The reason for emulsification and method improvement for vitamin E detection in fish oil health food]
Objective:
To evaluate the effect of EPA, DHA, DPA for emulsification and make improvements for vitamin E (VE) detection in fish oil health food.
Methods:
DHA, EPA and DPA were added to evaluate their effect for emulsification. Different methods to eliminate emulsification were compared. Ether, petroleum ether and cyclohexane were used for extraction and the results for VE determination were compared.
Results:
EPA and DHA were found to be able to increase emulsification. In case of emulsification, calcium chloride can be used to eliminate emulsification effectively. Compared to ether, petroleum ether was better in reducing emulsification and better extraction efficiency.
Conclusion:
It is recommended that petroleum ether should be used in VE detection in fish oil health food.

