Related Experiment Video
Updated: Apr 27, 2026
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
Fractures in children with cerebral palsy
1Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK, zulf.mughal@cmft.nhs.uk.
Children with cerebral palsy face a higher risk of fractures, especially in their lower limbs, due to low bone density. This review examines fracture causes and treatments for these children.
Area of Science:
- Pediatrics
- Orthopedics
- Neurology
Background:
- Children with moderate to severe cerebral palsy (CP) have an elevated risk of fractures from minor injuries.
- These fractures commonly affect lower limb bones and correlate with reduced bone mineral density (BMD).
Purpose of the Study:
- To review the prevalence and pathogenesis of fractures in nonambulant children with cerebral palsy.
- To discuss interventions and treatments aimed at improving BMD and reducing fracture risk in this population.
Main Methods:
- Literature review focusing on pediatric cerebral palsy and bone health.
- Analysis of risk factors, fracture patterns, and therapeutic strategies.
Main Results:
- Fractures in nonambulant children with CP are linked to factors like immobility, anticonvulsant medication, joint contractures, and poor nutrition.
- Low BMD is a significant contributing factor to fracture incidence.
Conclusions:
- Understanding fracture risk factors and pathogenesis is crucial for managing children with CP.
- Interventions targeting BMD may mitigate fracture risk in this vulnerable group.
More Related Videos
08:26Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
Published on: January 11, 2016
07:20Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
Published on: August 9, 2024
Related Concept Videos
01:27Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
01:24Flail Chest-I
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...