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Small incision iris tumour biopsy using a cavernous sampling forceps.

Argyrios Chronopoulos1, Ergin Kilic1, Antonia M Joussen1

  • 1Depatment of Ophthalmology, Charité University Medicine Berlin, Berlin, Germany Institute for Pathology, Charité University Medicine Berlin, Berlin, Germany.

The British Journal of Ophthalmology
|June 27, 2014
PubMed
Summary

Biopsies of pigmented iris tumors using the Essen-23G forceps achieved precise diagnosis in most cases with minimal complications. This technique offers a safe and effective method for intraocular tissue sampling.

Keywords:
IrisNeoplasiaPathology

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Area of Science:

  • Ophthalmology
  • Ophthalmic Surgery
  • Oncology

Background:

  • Pigmented iris tumors require accurate diagnosis.
  • Biopsy is crucial for definitive diagnosis of suspicious iris lesions.
  • Evaluating novel surgical tools for intraocular biopsies is essential.

Purpose of the Study:

  • To report the experience with the Essen-23G biopsy forceps for iris tumor biopsies.
  • To assess the efficacy and safety of the Essen-23G forceps in obtaining tissue samples from iris tumors.
  • To evaluate the diagnostic yield and complication rates associated with this biopsy technique.

Main Methods:

  • Retrospective study of patients with iris tumors undergoing biopsy between October 2012 and September 2013.
  • Utilized the Essen-23G biopsy forceps through a clear corneal incision for tissue extraction.
  • Employed a bimanual technique with 23G mini-scissors via a second incision in select cases for tissue manipulation.
  • Submitted tissue samples for histopathological and immunohistochemical evaluation.

Main Results:

  • Seven eyes of seven patients underwent biopsy with the Essen-23G forceps.
  • The average iris tumor thickness was 1.07±0.79 mm.
  • A precise histological and immunohistochemical diagnosis was achieved in 85% of cases.
  • Complications were minimal, including minor bleeding and one case of anisocoria without refractive issues.

Conclusions:

  • Iris tumor biopsies using the 23G intraocular forceps are feasible and safe.
  • The forceps design facilitates removal of intact tissue pieces with minimal artifacts.
  • An optional bimanual approach with 23G scissors enhances procedural efficacy.