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Related Experiment Videos

Meningioangiomatosis: a case report.

S S Liu1, P C Johnson, V K Sonntag

  • 1Division of Neurological Surgery, Barrow Neurological Institute, Phoenix, Arizona.

Surgical Neurology
|May 1, 1989
PubMed
Summary

Meningioangiomatosis, a rare disorder, typically affects young adults and causes seizures. Surgical resection of these benign brain lesions often resolves symptoms, even in cases without neurofibromatosis.

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Area of Science:

  • Neurology
  • Neurosurgery
  • Pathology

Background:

  • Meningioangiomatosis is a rare, benign neoplastic proliferation of meningothelial and vascular elements.
  • It typically presents in young adults with neurological symptoms, most commonly seizures.
  • While often associated with neurofibromatosis, cases without this comorbidity are documented.

Observation:

  • This report details a case of meningioangiomatosis occurring independently of neurofibromatosis.
  • The lesion was characterized as firm, well-demarcated, and containing areas of calcification.
  • Neurofibrillary tangles were observed within the lesion, a finding noted in prior literature but of uncertain significance.

Findings:

  • The patient, a young adult, presented with seizures attributable to the meningioangiomatosis lesion.
  • Surgical intervention, involving partial or total resection of the lesion, led to seizure resolution.
  • The benign nature of the lesion was confirmed histopathologically.

Implications:

  • This case reinforces that meningioangiomatosis can occur without neurofibromatosis.
  • Surgical resection is an effective treatment for seizure control in meningioangiomatosis.
  • Further research may elucidate the role of neurofibrillary tangles in the pathogenesis of this disorder.

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