Related Experiment Video
Updated: Apr 27, 2026
Bridging the Bio-Electronic Interface with Biofabrication
Published on: June 6, 2012
A photoresponsive glycosidase mimic
Mousumi Samanta1, V Siva Rama Krishna, Subhajit Bandyopadhyay
1Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, WB 741246, India. sb1@iiserkol.ac.in.
Abstract:
Azobenzene-3,3'-dicarboxylic acid exists in photoisomerizable (E) and (Z)-forms. Deprotonation of the carboxylic acid groups from the (E)-form occurs simultaneously, whereas in the (Z)-form it occurs in a stepwise fashion. The mono anionic form of the (Z)-isomer acts as a glycosidase mimic that proceeds through a general acid-general base catalytic mechanism. This is the first example of a photoresponsive glycosidase mimic.
