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Alcohol consumption, specific alcoholic beverages, and abdominal aortic aneurysm
Otto Stackelberg1, Martin Björck2, Susanna C Larsson2
1From the Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (O.S., S.C.L., N.O., A.W.); and the Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden (M.B.). otto.stackelberg@ki.se.
Circulation
|June 27, 2014
Summary
Moderate alcohol consumption, like beer and wine, may lower the risk of abdominal aortic aneurysm (AAA). More research is needed on higher alcohol intake and AAA development.
Area of Science:
- Cardiovascular Epidemiology
- Vascular Disease Research
- Alcohol Consumption Studies
Background:
- Limited research exists on alcohol's impact on abdominal aortic aneurysm (AAA) development.
- Investigating the relationship between alcohol intake and AAA hazard is crucial.
Purpose of the Study:
- To examine the association between total alcohol consumption and specific beverages with the risk of developing AAA.
- To analyze data from large Swedish cohorts to understand alcohol-AAA links.
Main Methods:
- Utilized Cox proportional hazards models on data from the Cohort of Swedish Men and Swedish Mammography Cohort.
- Assessed alcohol consumption via food frequency questionnaires and AAA incidence through national health registers.
- Followed over 80,000 participants for 14 years to identify AAA occurrences.
Main Results:
- A reduced hazard of AAA was observed with moderate alcohol consumption: 10 glasses/week for men (HR 0.80) and 5 glasses/week for women (HR 0.57).
- Beer consumption in men and wine consumption in women showed inverse associations with AAA risk.
- No significant association between liquor consumption and AAA risk was found.
Conclusions:
- Moderate intake of beer and wine is linked to a decreased risk of abdominal aortic aneurysm.
- The impact of higher alcohol consumption levels on AAA risk remains undetermined.
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