TRPV2 in the development of experimental colitis.

C M Issa1, B D Hambly, Y Wang

  • 1School of Life Science and Technology, TongJi University, Shanghai, China; Discipline of Pathology, Bosch Institute and School of Medical Sciences, University of Sydney, Sydney, NSW, Australia.

Summary

Transient receptor potential vanilloid 2 (TRPV2) deficiency reduces colitis severity in mice. This suggests TRPV2 plays a key role in intestinal inflammation and offers potential therapeutic targets for colitis.

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