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Related Concept Videos

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Related Experiment Video

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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
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Testing an innovative device against airborne Aspergillus contamination.

Guillaume Desoubeaux1, Marie-Charlotte Bernard2, Valérie Gros3

  • 1Department of Parasitology-Mycology-Tropical Medicine, Centre Hospitalier Régional Universitaire, Tours, France Unité Mixte de Recherche, Institut National de la Santé et de la Recherche Médicale U1100, Equipe d'Accueil 6305, University of François Rabelais School of Medicine, Tours, France.

Medical Mycology
|June 27, 2014
PubMed
Summary

This study shows a new mobile air purifier effectively removed Aspergillus fumigatus (a common airborne pathogen) from a hospital room simulation. The device significantly reduced fungal contamination, offering a potential tool for infection control.

Keywords:
Aspergillusindoor air contaminationmobile air purifiernosocomial infectionsphotocatalysistitanium

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Area of Science:

  • Environmental Microbiology
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Aspergillus fumigatus is a significant airborne nosocomial pathogen causing severe mycosis in immunocompromised individuals.
  • Controlling airborne fungal contamination is crucial in healthcare settings to prevent patient infections.

Purpose of the Study:

  • To evaluate the efficacy of an innovative mobile air-treatment device in eliminating airborne Aspergillus fumigatus.
  • To assess the device's performance in a controlled experimental setting mimicking a hospital room.

Main Methods:

  • Experimental massive contamination of a high-security room with Aspergillus fumigatus.
  • Sequential air sampling to isolate and quantify viable mycological particles.
  • Utilizing a mobile air purifier combining germicidal UV-C irradiation and titanium photocatalysis.

Main Results:

  • The mobile air purifier reduced airborne conidia concentration by 95% within 18 minutes.
  • Complete elimination below the detection threshold was achieved in 29 minutes, even at the lowest setting.
  • Spontaneous settling without air treatment showed conidia remaining airborne for over an hour.

Conclusions:

  • The tested air purifier demonstrated high effectiveness in eliminating Aspergillus conidia from indoor air.
  • This mobile device shows promise for routine use in reducing microbiological air contamination in patient rooms.
  • The findings suggest potential for preventing air-transmitted diseases caused by fungal pathogens.