Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

17
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
17
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

8.0K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
8.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A layered standards framework for integrating single-cell and spatial omics data into brain cell atlases.

bioRxiv : the preprint server for biology·2026
Same author

A Community Standard Multispecies Cell Atlas of the Basal Ganglia.

bioRxiv : the preprint server for biology·2026
Same author

Identification of Biological Subtypes of Friedreich Ataxia with Structural MRI-based Machine Learning.

Radiology·2026
Same author

Shape matters: Predicting Huntington's disease using progression modelling.

Computer methods and programs in biomedicine·2026
Same author

Pilot randomised controlled trial of a novel form of exercise on parkinsonism symptoms.

BMJ neurology open·2026
Same author

Widening access to penicillin allergy assessment in the United Kingdom-a proposed implementation plan for the National Health Service (NHS).

JAC-antimicrobial resistance·2026

Related Experiment Video

Updated: Apr 27, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K

Concurrent motor and cognitive function in multiple sclerosis: a motor overflow and motor stability study.

Anne-Marie Ternes1, Joanne Fielding, Patricia K Addamo

  • 1*Experimental Neuropsychology Research Unit †Ocular Motor Research Laboratory, School of Psychological Sciences, Monash University, Clayton Campus, Victoria, Australia ‡Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria, Australia §Institute of Sport, Exercise, and Active Living, Victoria University, Footscray Park Campus, Victoria, Australia.

Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology
|June 27, 2014
PubMed
Summary

Patients with multiple sclerosis (MS) showed similar effects of concurrent cognitive tasks on motor control as healthy individuals. This suggests preserved motor function in dual-tasking scenarios, aiding rehabilitation strategies.

More Related Videos

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

8.8K
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.1K

Related Experiment Videos

Last Updated: Apr 27, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

8.8K
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.1K

Area of Science:

  • Neuroscience
  • Motor Control
  • Cognitive Psychology

Background:

  • The interaction between motor and cognitive functions during concurrent task performance is complex and varies across populations.
  • Understanding these interactions is crucial, especially in clinical populations like those with multiple sclerosis (MS).

Purpose of the Study:

  • To investigate the impact of a concurrent digit span task on motor stability and motor overflow in patients with MS.
  • To compare motor performance during single-task versus dual-task conditions in MS patients and healthy controls.

Main Methods:

  • 22 patients with MS and 22 matched controls performed index finger force production tasks.
  • Motor stability (force accuracy) and motor overflow (involuntary force in the non-performing finger) were measured.
  • A digit span task was concurrently performed during half of the trials.

Main Results:

  • Patients with MS exhibited greater motor overflow and reduced motor stability compared to controls, correlating with disease severity.
  • Concurrent task performance modulated motor stability, with effects dependent on force exertion levels.
  • Motor overflow decreased during concurrent task trials, similarly for both MS patients and controls.

Conclusions:

  • Patients with MS demonstrate preserved motor function within a concurrent-task paradigm.
  • The study highlights the relationship between attention and motor control in both healthy individuals and MS patients.
  • Findings may inform rehabilitation strategies for daily life activities requiring simultaneous cognitive and motor engagement.