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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

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Prevention of thromboembolic complication in atrial fibrillation by using anticoagulants

Kunal Wagh, V B Vikhe, R Santosh Kumar

    The Journal of the Association of Physicians of India
    |June 28, 2014
    PubMed

    Insights

    Warfarin significantly reduces stroke risk in adults with atrial fibrillation (AF). This study found fewer strokes in AF patients taking warfarin compared to those not on the medication.

    Area of Science:

    • Cardiology
    • Neurology
    • Pharmacology

    Background:

    • Atrial fibrillation (AF) is a prevalent cardiac arrhythmia.
    • AF increases the risk of thromboembolic events, including stroke.
    • AF can manifest as paroxysmal or permanent conditions.

    Purpose of the Study:

    • To evaluate the efficacy of warfarin in mitigating stroke incidence among atrial fibrillation patients.
    • Assessing the protective effect of warfarin against stroke in a clinical setting.

    Main Methods:

    • A hospital-based case study was conducted.
    • The study included 50 patients diagnosed with atrial fibrillation.
    • Data was collected between October 2009 and September 2011.

    Main Results:

    • Out of 50 patients, 10 developed stroke.
    • None of the patients who developed stroke were on warfarin.
    • 32 patients on warfarin did not experience a stroke.

    Conclusions:

    • Warfarin demonstrates significant effectiveness in reducing stroke incidence in patients with atrial fibrillation.
    • The findings support the use of warfarin for stroke prevention in AF management.
    Abstract

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