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Azoospermic infertile men.

M T Mbizvo1, T H Chimbira, N J Gwavava

  • 1Department of Obstetrics and Gynaecology, University of Zimbabwe, Harare.

British Journal of Urology
|April 1, 1989
PubMed
Summary

A high incidence of azoospermia (sperm absence) was found in 24% of infertile men. Common causes included testicular failure, duct obstruction, and infections, with many reporting prior sexually transmitted infections.

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Area of Science:

  • Reproductive Medicine
  • Urology
  • Andrology

Background:

  • Infertility affects a significant number of men seeking medical help.
  • Azoospermia, the complete absence of spermatozoa in semen, is a key diagnosis in male infertility.
  • Previous studies report lower incidences of azoospermia compared to recent findings.

Purpose of the Study:

  • To determine the incidence of azoospermia in a cohort of infertile men.
  • To identify common etiological factors contributing to azoospermia in this population.
  • To understand the patient's perspective on treatment options for infertility.

Main Methods:

  • Retrospective analysis of 1518 consecutive cases of men referred for infertility.
  • Clinical evaluation including history, physical examination, and semen analysis.
  • Categorization of causes based on testicular failure, ductal obstruction, endocrine issues, cryptorchidism, and infection.

Main Results:

  • A high incidence of 24% (369 out of 1518 men) presented with azoospermia.
  • Primary testicular failure, ductal obstruction, endocrine abnormalities, cryptorchidism, and infection were frequently observed.
  • A history of sexually transmitted infection was reported by 67% of men with azoospermia.

Conclusions:

  • The incidence of azoospermia in this referred male infertility population is notably high.
  • Multiple factors contribute to azoospermia, with a significant association with prior sexually transmitted infections.
  • Patient acceptance of alternative reproductive options like donor insemination or adoption remains very low.

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