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Updated: Apr 27, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Iron or boron-catalyzed C-H arylthiation of substituted phenols at room temperature
Hua Tian1, Changjin Zhu, Haijun Yang
1Department of Applied Chemistry, Beijing Institute of Technology, Beijing 100081, P. R. China.
Abstract:
A simple, efficient and environmentally friendly method for iron or boron-catalyzed C-H arylthiation of substituted phenols at room temperature has been developed, and the corresponding diaryl sulfides were prepared in good to excellent yields. The protocol uses readily available 1-(substituted phenylthio)pyrrolidine-2,5-diones as the arylthiation reagents and inexpensive and environmentally friendly FeCl3 or BF3·OEt2 as the catalyst, moreover no ligands, additives or extrusion of air are required, and the reactions can be performed successfully at room temperature.
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