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Updated: Aug 10, 2026
12:53
Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
Pattern of lymph node pathology in western Saudi Arabia
Abdulkader Mohammed Albasri1, Abeer Abdalla El-Siddig, Akbar Shah Hussainy
1Department of Pathology, Taibah University, King Fahad Hospital, Madinah, Saudi Arabia
Asian Pacific Journal of Cancer Prevention : APJCP
|June 28, 2014
Summary
Lymph node biopsies in Saudi Arabia revealed malignant lymphomas as the most frequent cause of enlargement, particularly in older adults. Reactive hyperplasia and tuberculosis were common in younger patients.
Area of Science:
- Pathology
- Oncology
- Infectious Diseases
Background:
- Lymphadenopathy is a common clinical finding requiring histopathological evaluation.
- Understanding regional variations in lymph node pathology is crucial for accurate diagnosis and management.
Purpose of the Study:
- To characterize the histopathological patterns of lymph node pathology in Saudi patients.
- To analyze age and gender variations in lymph node lesions.
Main Methods:
- Retrospective analysis of lymph node biopsy specimens.
- Data collected from King Fahad Hospital, Madinah, Saudi Arabia (January 2006 - December 2013).
Main Results:
- Malignant lymphomas (44.3%) were the most common diagnosis, followed by reactive hyperplasia (23.5%) and tuberculosis (14.2%).
- Hodgkin's disease, reactive hyperplasia, and tuberculosis were prevalent in younger adults (10-29 years).
- Non-Hodgkin's lymphoma predominated in patients over 50 years old.
Conclusions:
- Lymph node biopsy is essential for diagnosing lymphadenopathy causes.
- Lymphomas are the leading cause of lymph node enlargement in this Saudi cohort.
- Age-specific patterns exist for different lymph node pathologies.
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