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Updated: Apr 27, 2026
Multifocal Electroretinograms
Published on: December 4, 2011
Multifocal electroretinograms in Stargardt's disease/fundus flavimaculatus
Kazuki Kuniyoshi1, Hiroko Terasaki, Mikki Arai
1Schepens Eye Research Institute, Harvard Medical School, Boston, Mass., USA.
Purpose:
To determine whether the characteristics of multifocal electroretinograms (mfERGs) were correlated with the ophthalmic appearance of the fundus in patients with Stargardt's disease/fundus flavimaculatus (SFF).
Methods:
Full-field ERGs, mfERGs, and general ophthalmic examinations were performed on 49 eyes with SFF.
Results:
The SFF patients were divided into four subtypes according to the classification of Noble and Carr [Arch Ophthalmol 1979;97:1281-1285]. The patients with type 1 SFF had severely reduced mfERGs in the macular area and reduced and delayed responses in the mid-periphery. The type 2 SFF patients had reduced but recordable mfERGs from the center of the macula with more depressed responses in the paramacular area, and the type 3 SFF patients had reduced and delayed mfERGs both in the macula and periphery. The patients with type 4 SFF had normal mfERGs in the macular area and delayed responses in all outer zones.
Conclusions:
These mfERG findings indicate that each subtype of SFF has unique characteristics corresponding to the abnormal retinal functions.
