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99mTc(Cu)-mannitol complex: a new agent for dynamic renal function studies
U P Chauhan1, J Chander, P Mishra
1Institute of Nuclear Medicine and Allied Sciences, Delhi-, India.
International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology
|January 1, 1989
Abstract:
Mannitol has been labeled with 99mTc by using cuprous chloride as a reducing agent. Blood and kidney clearance of 99mTc(Cu)-mannitol was slightly faster than that of 99mTc(Sn)-DPTA in rat and maximum radioactivity ratio of kidneys to blood was 84.6 at 5 min. A comparative study of 99mTc(Cu)-mannitol, 99mTc(Sn)-DTPA was made in rabbits by taking serial images of kidneys and bladder with a gamma camera. Results show superiority of 99mTc(Cu)-mannitol over other agents for dynamic renal function studies.