Intracranial pressure at altitude

Mark H Wilson1, Alex Wright, Christopher H E Imray

  • 11 The Brain Injury Centre-St Mary's Hospital , Imperial College, London, United Kingdom .

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Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
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