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Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
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Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
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Metastatic malignant melanoma causing ileo-ileal intussusception.

D Yerrakalva1, R Ackroyd1, F Lee1

  • 1Northern General Hospital, Sheffield, UK.

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A rare case of metastatic malignant melanoma caused ileo-ileal intussusception in a 66-year-old man. This highlights the importance of investigating gastrointestinal symptoms in melanoma patients due to silent metastases.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Pathology

Background:

  • Malignant melanoma can metastasize to the gastrointestinal tract, often asymptomatically.
  • Intussusception is an uncommon cause of intestinal obstruction in adults.

Purpose of the Study:

  • To report a rare case of ileo-ileal intussusception caused by metastatic malignant melanoma.
  • To emphasize the significance of gastrointestinal symptoms in patients with a history of melanoma.

Main Methods:

  • Case report of a 66-year-old male patient.
  • Diagnostic imaging including CT scan.
  • Surgical resection and histological analysis.

Main Results:

  • The patient presented with symptoms of small bowel obstruction.
  • CT scan revealed a nodular intussusception.
  • Histological analysis confirmed metastatic malignant melanoma as the lead point of intussusception.

Conclusions:

  • Metastatic malignant melanoma can present as intussusception, a rare cause of bowel obstruction.
  • Patients with a history of melanoma presenting with gastrointestinal symptoms require thorough evaluation due to the potential for silent metastases.