Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

138
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
138
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

29
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
29
Reticular Dermis01:15

Reticular Dermis

4.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
4.6K
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

1.9K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.9K
Acne Infection01:27

Acne Infection

91
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
91

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of 16S rRNA gene amplicon sequencing in the investigation of novel ovine skin lesions in Norway.

Frontiers in veterinary science·2026
Same author

Ovine lameness in Ireland: a survey-based investigation of farmer reported prevalence, recognition, and treatment of lameness conditions.

Irish veterinary journal·2025
Same author

JWST Observations of Segregated <sup>12</sup>CO<sub>2</sub> and <sup>13</sup>CO<sub>2</sub> Ices in Protostellar Envelopes.

ACS earth & space chemistry·2025
Same author

Evaluation of milking performance following 2 different teat-preparation routines.

Journal of dairy science·2025
Same author

The development, validation and application of an indirect enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Streptococcus dysgalactiae subspecies dysgalactiae in lamb and ewe sera.

Research in veterinary science·2025
Same author

A cross-sectional survey of farmer reported prevalence and farm management practices associated with neonatal infectious arthritis ("joint ill") in lambs, on UK sheep farms.

Frontiers in veterinary science·2025

Related Experiment Video

Updated: Apr 27, 2026

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
08:30

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

2.0K

Contagious ovine digital dermatitis: an emerging disease.

J S Duncan1, J W Angell1, S D Carter2

  • 1Department of Epidemiology and Population Health, Institute of Infection and Global Health, University of Liverpool, Leahurst Campus, Neston, Wirral CH64 7TE, UK.

Veterinary Journal (London, England : 1997)
|June 29, 2014
PubMed
Summary

Contagious ovine digital dermatitis (CODD) is an emerging sheep disease causing severe lameness. Amoxicillin shows efficacy, but more research is needed for control and prevention strategies.

Keywords:
Contagious ovine digital dermatitis (CODD)FootrotLamenessSheepWelfare

More Related Videos

Intravitreal Injections in the Ovine Eye
03:37

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

3.6K
Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
13:42

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep

Published on: January 19, 2014

16.1K

Related Experiment Videos

Last Updated: Apr 27, 2026

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
08:30

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

2.0K
Intravitreal Injections in the Ovine Eye
03:37

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

3.6K
Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
13:42

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep

Published on: January 19, 2014

16.1K

Area of Science:

  • Veterinary Medicine
  • Animal Pathology
  • Microbiology

Background:

  • Contagious ovine digital dermatitis (CODD) is a novel sheep disease first identified in the UK in 1997.
  • CODD presents as severe lameness due to hoof capsule separation, with treponeme bacteria frequently isolated.
  • The prevalence of CODD is increasing, yet transmission routes and risk factors remain unclear.

Purpose of the Study:

  • To review current knowledge on the clinical, etiological, and epidemiological aspects of CODD.
  • To assess current and potential control strategies for CODD.
  • To highlight areas requiring further research for sustainable CODD management.

Main Methods:

  • Literature review of clinical observations, microbiological findings, and epidemiological data on CODD.
  • Analysis of evidence-based treatment trials for CODD.
  • Assessment of proposed control measures, including biosecurity and vaccine development.

Main Results:

  • Treponeme bacteria, similar to those in bovine digital dermatitis (BDD), are commonly found in CODD lesions.
  • Parenteral long-acting amoxicillin is an effective treatment for CODD.
  • Further research into microbiology, epidemiology, and control is essential.

Conclusions:

  • CODD is a significant and growing concern in sheep farming.
  • Effective treatment options exist, but comprehensive control strategies are lacking.
  • Urgent research is needed to understand transmission, develop vaccines, and implement biosecurity protocols.