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A Fluorescence-based Assay of Phospholipid Scramblase Activity
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Phospholipid scrambling on the plasma membrane

Jun Suzuki1, Shigekazu Nagata1

  • 1Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Methods in Enzymology
|June 30, 2014
PubMed
Summary

Phospholipid scrambling, crucial for cell signaling, is mediated by two distinct protein families. TMEM16F protein regulates scrambling in blood clotting, while XK-related family protein 8 controls it during apoptosis.

Keywords:
PhosphatidylcholinePhosphatidylserinePhospholipidScramblaseTMEM16FXkr8

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