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Updated: Apr 27, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Image-enhanced endoscopy is critical in the surveillance of patients with colonic IBD
Venkataraman Subramanian1, Raf Bisschops2
1Molecular Gastroenterology, Leeds Institute of Biomedical and Clinical Sciences, St James University Hospital, University of Leeds, Leeds LS9 7TF, UK.
Abstract:
Cancer risk in patients with inflammatory bowel disease (IBD) involving the colon is high and increases with time. The quality and efficacy of colonoscopic surveillance is variable. Chromoendoscopy with targeted biopsies is superior to standard white light endoscopy with random biopsies. Although commonly practiced, the technique of random colonic biopsies has poor yield for dysplasia and has little clinical consequence. Studies have shown a limited role for electronic-based image-enhanced endoscopy, including narrow band imaging, in detecting IBD dysplasia. Efforts should focus on the dissemination of the technique of chromoendoscopy in routine clinical practice through training and quality metrics.
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