The evaluation of preoperative right ventricular diastolic dysfunction on coronary artery disease patients with left

Yan Jin1, Huishan Wang, Zengwei Wang

  • 1Department of Cardiac Surgery, General Hospital of Shenyang Military Area Command, Shenyang City, China.

Insights

Early death after coronary artery bypass graft (CABG) surgery in patients with poor left ventricular function is linked to impaired right ventricular diastolic function and few bypass targets. Preoperative RV diastolic assessment aids in predicting mortality risk.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Echocardiography

Background:

  • Coronary artery bypass graft (CABG) surgery is a common treatment for coronary heart disease (CHD).
  • Patients with severely impaired left ventricular function (LVEF ≤ 35%) face higher risks of early death post-CABG.
  • Identifying predictors of early mortality in this high-risk group is crucial.

Purpose of the Study:

  • To identify independent risk factors for early death after CABG in patients with severely impaired left ventricular function.
  • To evaluate the predictive value of preoperative right ventricular (RV) diastolic function for early mortality.

Main Methods:

  • Retrospective analysis of 231 patients undergoing CABG with LVEF ≤ 35% from June 2007 to October 2012.
  • Patients were divided into two groups: early death (n=39) and successful outcome (n=192).
  • Multivariate analysis was used to determine independent risk factors.

Main Results:

  • Significantly decreased preoperative right ventricular (RV) diastolic function (increase in Et/Et') and lack of suitable target bypass vessels were independent risk factors for early death (P = 0.003 and 0.002).
  • Preoperative Et/Et' ≥ 10 was significantly associated with early death (OR = 17.54, P < 0.001).
  • Age, IABP, IMR treatment, and left atrial/ventricular dimensions were not associated with early death.

Conclusions:

  • Decreased preoperative RV diastolic function and insufficient target bypass vessels are key predictors of early death post-CABG in patients with severely impaired left ventricular function.
  • Preoperative RV diastolic function assessment, particularly Et/Et' ≥ 10, is valuable for predicting early mortality in this patient cohort.
  • These findings can help optimize surgical planning and patient selection for CABG.
Abstract

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