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Pearl shaped highly sensitive Mn3O4 nanocomposite interface for biosensor applications
K Kamil Reza1, Nawab Singh1, Surendra K Yadav1
1Biomedical Instrumentation Section, National Physical Laboratory (CSIR), Dr. K.S. Krishnan Marg, New Delhi 110012, India.
Abstract:
An electrochemical biosensor based on manganese oxide (Mn3O4) and chitosan (Cn) nanocomposite has been fabricated for fish freshness detection. The electrophoretic deposition of Mn3O4 nanoparticles (15-20 nm) with Cn has changed their morphological arrangement leading to pearl shaped of Mn3O4-Cn nanocomposite on indium tin oxide substrate. Size and morphology of nanocomposite have been confirmed by high resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results of electrochemical response reveal that this improved sensor has widest detection range of xanthine concentration from 1 to 500 µM and excellent sensitivity of 1.46 μA µM(-1) cm(-2). The fabricated XOx/Mn3O4-Cn/ITO biosensor can detect as low as 1.31 μM of xanthine and lower Km value of 0.018 μM confirming its superior affinity towards the nanocomposite film.
