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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Hepatitis01:25

Hepatitis

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

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Hepatobiliary tuberculosis.

Poras Chaudhary1

  • 1Department of Surgery, Dr Ram Manohar Lohia Hospital (Dr RMLH and PGIMER), New Delhi, India.

Annals of Gastroenterology
|July 1, 2014
PubMed
Summary
This summary is machine-generated.

Hepatobiliary tuberculosis, a rare Mycobacterium tuberculosis infection, presents diagnostic challenges due to non-specific symptoms. Early diagnosis and treatment with antitubercular drugs and surgery improve prognosis.

Keywords:
Hepatobiliary tuberculosisantituberculous drugsdifficult diagnosishistopathology

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Microbiology

Background:

  • Hepatobiliary tuberculosis is an uncommon form of Mycobacterium tuberculosis infection, often secondary to pulmonary or gastrointestinal tuberculosis.
  • Diagnosis is challenging due to rarity, non-specific symptoms, and limited imaging criteria, especially for focal presentations.
  • Definitive diagnosis typically requires histopathology, but PCR assays offer potential for pre-operative identification.

Approach:

  • Review of current knowledge and literature on hepatobiliary tuberculosis.
  • Analysis of diagnostic challenges and treatment strategies.
  • Presentation of clinical cases to illustrate disease characteristics.

Key Points:

  • Hepatobiliary tuberculosis diagnosis is difficult pre-operatively due to non-specific presentations.
  • Polymerase Chain Reaction (PCR) assays can aid in pre-operative diagnosis.
  • Treatment involves conventional antitubercular drugs, with surgery for abscesses or granulomas.
  • Prognosis is generally good with complete antitubercular therapy.

Conclusions:

  • Hepatobiliary tuberculosis requires a high index of suspicion for timely diagnosis.
  • Multidisciplinary approach combining medical and surgical interventions is crucial.
  • Further research into improved diagnostic modalities is warranted.