Related Experiment Video
Updated: Apr 27, 2026
The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Endoscopic submucosal dissection: experience in an Australian tertiary center
Prayman T Sattianayagam1, Paul V Desmond2, Chatura Jayasekera2
1Department of Gastroenterology, East Kent Hospitals University Foundation Trust, UK (Prayman T. Sattianayagam) ; Department of Gastroenterology, St. Vincent's Hospital, Melbourne, Australia (Prayman T. Sattianayagam, Paul V. Desmond, Chatura Jayasekera, Robert Y. Chen).
Endoscopic submucosal dissection (ESD) is a feasible endoscopic resection technique for gastrointestinal tumors in Australia. Careful patient selection and technique refinement are recommended for optimal outcomes with this advanced procedure.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Oncology
Background:
- Endoscopic submucosal dissection (ESD) is an advanced technique for en bloc resection of superficial gastrointestinal tumors.
- Limited data exists on ESD outcomes in Western countries compared to Asian nations.
- This study evaluates the initial experience with ESD in an Australian tertiary center.
Purpose of the Study:
- To assess the feasibility and outcomes of endoscopic submucosal dissection (ESD) for gastrointestinal tumors in Australia.
- To report on patient characteristics, procedural success rates, and complications associated with ESD.
- To provide insights into the application of ESD in a Western healthcare setting.
Main Methods:
- Retrospective review of 20 endoscopic submucosal dissection (ESD) procedures performed between 2008 and 2012.
- Analysis of patient demographics, lesion characteristics, and tumor locations (gastric, rectal, colonic, duodenal, esophageal).
- Evaluation of en bloc resection rates, complete histological resection, and complication incidence.
Main Results:
- Twenty lesions were resected in 18 patients (median age 69.5 years).
- En bloc resection was achieved in 80% of cases, with complete histological resection in 60%.
- Complications included significant bleeding (2 cases) and microscopic perforation (1 case); 6 patients required subsequent surgery.
Conclusions:
- Endoscopic submucosal dissection (ESD) is a feasible technique for gastrointestinal tumor resection in an Australian population.
- Careful patient selection and optimization of ESD technique and complication management are crucial.
- Further experience is needed to refine the application of ESD in this setting.
