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Does bleeding affect fetal Doppler parameters during genetic amniocentesis?
Cantekin Iskender1, Ebru Tarım2, Tayfun Cok2
1Department of Perinatology, Dr Zekai Tahir Burak Research and Training Hospital, Ankara, Turkey.
Objective:
The aim of this study was to investigate the relationship between fetal Doppler parameters and bleeding at insertion points during amniocentesis.
Material And Methods:
This prospective study was conducted between July 2010 and February 2011. A total of 215 amniocentesis procedures were performed during this period. Five patients with Down syndrome were excluded from the study. The remaining 210 patients were divided into Group 1 (bleeding at insertion site) and Group 2 as a control group. One needle type was used for all patients. Umbilical artery resistance index (UARI), umbilical artery pulsatility index (UAPI), middle cerebral artery resistance index (MCARI), middle cerebral artery pulsatility index (MCA PI), and middle cerebral artery peak systolic velocity (MCAPSV) were measured immediately and before and after amniocentesis.
Results:
Bleeding at the insertion point during amniocentesis did not significantly change the UARI (34% increase for Group 1 and 46.5% increase for Group 2, p=0.238), the MCARI (52% increase for Group 1 and 45% increase for Group 2, p=0.622), or the MCAPSV (37% increase for Group 1 and 49% increase for Group 2, p=0.199). UARI, MCARI, MCA PI, and MCAPSV were not significantly altered following amniocentesis in Groups 1 and 2. There was a significant increase in UAPI following amniocentesis only in Group 2.
Conclusion:
Bleeding during genetic amniocentesis did not change umbilical artery and middle cerebral artery Doppler parameters.
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