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POPI (Pediatrics: Omission of Prescriptions and Inappropriate prescriptions): development of a tool to identify

Sonia Prot-Labarthe1, Thomas Weil2, François Angoulvant3

  • 1Pharmacie, AP-HP Hôpital Robert-Debré, Paris, France.

Plos One
|July 1, 2014
PubMed

Insights

A new tool, POPI, was developed to identify inappropriate prescriptions and drug omissions in children. This screening tool, based on expert consensus, aims to improve rational prescribing in pediatrics and reduce medication errors.

Area of Science:

  • Pediatric Pharmacology
  • Medication Safety
  • Health Informatics

Background:

  • Rational prescribing in children is a global challenge with insufficient research.
  • Medication errors, including inappropriate prescriptions and omissions, are prevalent in pediatric populations.
  • Existing guidelines require a dedicated screening tool for pediatric prescription analysis.

Purpose of the Study:

  • To develop a screening tool for identifying inappropriate prescriptions and drug omissions in pediatric care.
  • To base the tool on established French and international pediatric prescribing guidelines.
  • To enhance the safety and appropriateness of medication use in children.

Main Methods:

  • Disease selection based on social security and hospital statistics.
  • Literature review to identify explicit criteria for the POPI tool.
  • Two-round Delphi consensus technique with 16 expert panelists (pharmacists and pediatricians) using a 9-point Likert scale.

Main Results:

  • Developed 108 explicit criteria (80 for inappropriate prescriptions, 28 for omissions).
  • Criteria categorized by physiological systems (gastroenterology, respiratory, pain, neurology, dermatology, miscellaneous).
  • After two Delphi rounds, 104 criteria (79 inappropriate prescriptions, 25 omissions) were validated by experts.

Conclusions:

  • POPI is the first screening tool specifically designed to detect inappropriate prescriptions and omissions in pediatrics.
  • Further research, including inter-user reliability and prospective effectiveness studies, is required.
  • The tool aims to improve medication safety and rational prescribing practices in pediatric patients.
Abstract

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