Related Experiment Video
Updated: Apr 27, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Modern analytical technologies for the detection of drug abuse and doping
Marilyn A Huestis1, Michael L Smith2
1Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.
Abstract:
Consequences to individuals convicted of abusing prohibited drugs or doping agents can be severe, including loss of employment, child custody, driving privileges, right to compete in international sports and ultimately freedom, when mandatory confinement occurs. In view of these penalties, laboratories charged with providing evidence must maximize testing accuracy. False positive and false negative tests are prevented by combining sensitive immunoassays and specific chromatographic-mass spectrometric detection. In addition, testing different biological matrices offers unique information about the drug-use history of an individual.:
Related Concept Videos
High-Performance Liquid Chromatography: Types of Detectors
Therapeutic Drug Monitoring: Drug Analysis Methods
Drug Concentrations: Measurements
Plasma...
Automated Microbial Diagnostics
Mass Spectrometry: Complex Analysis
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
Drug Abuse and Addiction: Pharmacological Phenomena

