Experimental appendicitis and appendectomy modulate the CCL20-CCR6 axis to limit inflammatory colitis pathology

Rajkumar Cheluvappa1

  • 1Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, NSW, Australia, rajkumarchel@gmail.com.

Summary

Appendicitis and appendectomy (AA) in mice suppresses inflammatory pathways linked to inflammatory bowel diseases (IBD). This finding offers potential new strategies for managing IBD by targeting the CCL20-CCR6 axis and Th17 system.

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