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Comorbidity of ADHD and incontinence in children
Alexander von Gontard1, Monika Equit
1Department of Child and Adolescent Psychiatry, Saarland University Hospital, 66421, Homburg, Germany.
Insights
Attention-deficit/hyperactivity disorder (ADHD) and childhood incontinence, including nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI), frequently co-occur. Non-genetic factors likely explain this comorbidity, impacting treatment outcomes.
Area of Science:
- Pediatric medicine
- Child psychology
- Neurodevelopmental disorders
Background:
- Attention-deficit/hyperactivity disorder (ADHD) and various forms of childhood incontinence (nocturnal enuresis, daytime urinary incontinence, fecal incontinence) are prevalent and often coexist.
- The co-occurrence exceeds chance, suggesting shared underlying factors or influences.
Purpose of the Study:
- To review the comorbidity of ADHD with nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in children.
- To examine the prevalence of ADHD in children diagnosed with NE, DUI, and FI.
Main Methods:
- Literature review synthesizing findings from clinical and population-based studies.
- Examination of genetic, neurophysiological, imaging, and pharmacological research.
Main Results:
- ADHD and NE are commonly studied together, but DUI presents a higher risk for ADHD.
- Children with FI show high rates of psychological disorders, though not exclusively ADHD.
- Genetic studies suggest ADHD and incontinence types do not share a genetic basis; non-genetic factors are implicated.
- Neurophysiological, imaging, and pharmacological studies offer potential links between ADHD and incontinence.
Conclusions:
- The comorbidity of ADHD and incontinence is influenced by non-genetic factors.
- Children with both ADHD and incontinence present greater treatment challenges, including lower compliance and poorer outcomes.
- Integrated assessment and specific treatment approaches are necessary for children with co-occurring ADHD and incontinence.
Abstract:
ADHD and incontinence are common childhood disorders which co-occur at much higher rates than expected by chance. The aim of this review was to provide an overview both of the comorbidity of nocturnal enuresis (NE), daytime urinary incontinence (DUI) and faecal incontinence (FI) in children with ADHD; and, vice versa, of the co-occurrence of ADHD in children with NE, DUI and FI. Most clinical studies have focussed on the association of ADHD and NE. Population-based studies have shown that children with DUI have an even greater risk for ADHD than those with NE. While children with FI have the highest overall comorbidity rates of psychological disorders, these are heterogeneous with a wide range of internalising and externalising disorders--not necessarily of ADHD. Genetic studies indicate that ADHD and NE, DUI and FI do not share the same genetic basis. The comorbidity is conferred by non-genetic factors. Possible aetiological and pathogenetic links between ADHD and incontinence are provided by neurophysiological, imaging and pharmacological studies. The co-occurrence has clinical implications: children with ADHD and NE, DUI and FI are more difficult to treat, show lower compliance and have less favourable treatment outcomes for incontinence. Therefore, both groups of disorders have to be assessed and treated specifically.
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