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Updated: Apr 27, 2026
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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[New KDIGO guidelines on acute kidney injury. Practical recommendations]
1Klinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie, Universitätsklinikum Münster, Albert-Schweitzer Str. 33, 48149, Münster, Deutschland, zarbock@uni-muenster.de.
Der Anaesthesist
|July 2, 2014
Summary
Acute kidney injury (AKI) is common in critically ill patients. The KDIGO guidelines offer evidence-based recommendations for AKI management, focusing on early diagnosis and supportive care due to a lack of specific pharmacological treatments.
Area of Science:
- Nephrology
- Critical Care Medicine
Context:
- High incidence of acute kidney injury (AKI) in critically ill patients.
- Significant morbidity and mortality associated with AKI.
Purpose:
- To summarize the 2012 Kidney Disease: Improving Global Outcome (KDIGO) guidelines for AKI.
- Provide evidence-based recommendations for AKI evaluation and management.
Summary:
- KDIGO guidelines unify AKI definitions and staging criteria.
- Recommendations cover AKI prevention, treatment, and renal replacement therapy (RRT).
- Emphasizes early diagnosis, hemodynamic optimization, volume control, and avoiding nephrotoxins due to limited pharmacological options.
Impact:
- Guides clinical practice for AKI in critical care.
- Highlights areas with insufficient evidence for recommendations.
- Informs management strategies for RRT in AKI patients.
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