Candida vascular complication in a liver transplant recipient due to yeast contamination of preservation solution

Area of Science:

• Medicine
• Transplantation
• Infectious Diseases

Background:

• Infections are a significant cause of morbidity and mortality post-liver transplantation.
• Preservation fluid contamination is a potential source of post-transplant infections.
• Donor-derived pathogens, like Candida albicans, can lead to severe complications in organ recipients.

Observation:

• A case of liver graft loss occurred due to vascular complications.
• Candida albicans was identified in the preservation fluid, originating from the donor.

Findings:

• Donor-derived Candida albicans in preservation fluid led to severe vascular complications and graft failure.
• This case highlights a rare but life-threatening complication in liver transplant recipients.

Implications:

• Implementing early antifungal treatment and regular radiological monitoring, similar to renal transplantation protocols, may be beneficial.
• Proactive screening for donor-derived pathogens in preservation fluid could improve outcomes.