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Updated: Apr 27, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Capillary electrophoresis technologies for screening in drug discovery
Hong Wan1, Richard A Thompson1
1DMPK & Bioanalytical Chemistry, AstraZeneca R&D Mölndal, S-43183 Mölndal, Sweden.
Abstract:
The high separation efficiency of capillary electrophoresis (CE), combined with the high selectivity and sensitivity of mass spectrometry (MS) detection offers the potential of unique resolving power and high-throughput capacity to the analysis and structural identification of complex mixtures. Recent advances in CE-MS interfaces and commercially available 96-capillary instruments have made the implementation of routine CE methods for drug screening feasible.:
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