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Coumamidines, new broad spectrum antibiotics of the cinodine type. II. Isolation and structural elucidation
R H Chen1, D N Whittern, A M Buko
1Anti-infective Research, Abbott Laboratories, Abbott Park, Illinois 60064.
The Journal of Antibiotics
|April 1, 1989
Abstract:
Two novel, isomeric compounds, coumamidines gamma 1 and gamma 2, were isolated from fermentations of an actinomycete. The structures were elucidated spectroscopically using 2D NMR correlation experiments and mass spectral data. The coumamidines were found to be close structural relatives of the cinodines (LL-BM123 gamma 1 and gamma 2).