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Updated: Apr 27, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

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[Deep brain stimulation in psychiatry: ethical aspects].

Ulf J Müller¹, Bernhard Bogerts¹, Jürgen Voges²

¹Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Magdeburg.

Psychiatrische Praxis

|July 2, 2014

Summary

Deep brain stimulation (DBS) is an effective treatment for neurological and psychiatric conditions. This review examines ethical concerns and critiques regarding DBS in psychiatry, questioning the neurobiological basis of these disorders.

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Area of Science:

Neuroscience
Psychiatry
Medical Ethics

Context:

Deep brain stimulation (DBS) is an established treatment for neurological disorders.
The application of DBS has expanded to psychiatric conditions.
Ethical considerations are paramount in the clinical use of DBS.

Purpose:

To review the history and ethical concerns of DBS in psychiatry.
To analyze ethical issues related to clinical trial design and patient selection.
To discuss concerns regarding informed consent and personality changes.

Summary:

This review covers the historical use of DBS in psychiatry.
It details ethical challenges including trial design, patient selection, and informed consent.
Potential impacts on personality and the questioning of neurobiological origins of psychiatric disorders are highlighted.

Impact:

Provides a comprehensive overview of ethical considerations for DBS in psychiatric applications.
Informs clinicians and researchers about potential risks and societal concerns.
Contributes to the ongoing debate on the neurobiological underpinnings of psychiatric diseases.