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Published on: October 20, 2017
Endovascular management of cerebral venous sinus thrombosis
Omar Choudhri1, Abdullah Feroze, Michael P Marks
1Department of Neurosurgery & Interventional Neuroradiology, Stanford University Medical Centre, Stanford, California.
Insights
Cerebral venous sinus thrombosis (CVST) is a serious condition involving blood clots in the brain. This case study details successful endovascular treatment for widespread CVST, offering a potential alternative for complex cases.
Area of Science:
- Neurology
- Vascular Medicine
- Interventional Radiology
Background:
- Cerebral venous sinus thrombosis (CVST) involves thrombus formation in cerebral veins, leading to potential complications like hypertension, infarcts, hemorrhage, and seizures.
- Standard management for CVST typically involves systemic anticoagulation with heparin.
- Endovascular strategies are considered for patients with CVST who deteriorate clinically despite anticoagulation.
Observation:
- The case involves a patient with extensive CVST affecting the superior sagittal sinuses and bilateral transverse sigmoid sinuses.
- The patient experienced clinical deterioration despite receiving heparin therapy.
Findings:
- A combination of endovascular therapies was employed to recanalize the affected cerebral venous sinuses.
- Successful recanalization was achieved through the endovascular approach.
Implications:
- This case highlights the efficacy of combined endovascular therapies as a treatment option for complex and widespread CVST.
- The findings suggest that endovascular intervention can be a valuable strategy for managing refractory CVST cases.
- Further research into endovascular techniques for CVST may improve patient outcomes.
Abstract:
Cerebral venous sinus thrombosis (CVST) is characterized by formation of widespread thrombus within the cerebral venous sinus system. CVST can cause venous hypertension, venous infarcts, hemorrhage and seizures. It is managed in most cases with systemic anticoagulation through the use of heparin to resolve the thrombus. Patients that demonstrate clinical deterioration while on heparin are often treated with endovascular strategies to recanalize the sinuses. We present the case of a patient with widespread CVST, involving his superior sagittal sinuses and bilateral transverse sigmoid sinuses, who was treated with a combination of endovascular therapies. The video can be found here: http://youtu.be/w3wAGlT7h8c .
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