Related Experiment Video
Updated: Apr 27, 2026

Collection and Extraction of Saliva DNA for Next Generation Sequencing
Published on: August 27, 2014
Saliva as a source of genomic DNA for genetic studies: review of current methods and applications
Fanyue Sun, Ernst J Reichenberger1
1Department of Reconstructive Sciences, Center for Regenerative Medicine and Developmental Biology, University of Connecticut Health Center, Farmington, CT 06030-3705, USA; Tel: 860-679-2062; Fax: 860-679-2910;
Abstract:
DNA isolated from saliva has become an attractive alternative to the use of blood-derived DNA in genetic studies and is now extensively used in many applications. This review addresses advantages of saliva DNA for large population-based studies and points out caveats for use in certain techniques. We compiled data comparing saliva-derived genomic DNA to blood-derived DNA with regards to quality, quantity and convenience. Special attention is given to the usefulness of saliva-derived DNA for PCR-based methods and genome-wide analyses.
Related Concept Videos
DNA Isolation
Genomic DNA in Eukaryotes
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Salivary Glands and Saliva
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...

