Related Experiment Video
Updated: Aug 12, 2026

Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
Published on: August 16, 2011
Maternal transfer of resistance to Schistosoma mansoni
1Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912.
Infected mother rats, resistant to Schistosoma mansoni, yielded offspring that were significantly resistant to a primary infection with cercariae, demonstrating the maternal transfer of protection. Newborns of normal mother rats could also be made resistant by the injection of protective immune rat serum, indicating that the effector phase components required for expression of protective activity are present in the newborn rat. The injection of the protective antiserum into newborns of the infected mothers enhanced resistance to a level exceeding 90%.
Infected mother rats, resistant to Schistosoma mansoni, yielded offspring that were significantly resistant to a primary infection with cercariae, demonstrating the maternal transfer of protection. Newborns of normal mother rats could also be made resistant by the injection of protective immune rat serum, indicating that the effector phase components required for expression of protective activity are present in the newborn rat. The injection of the protective antiserum into newborns of the infected mothers enhanced resistance to a level exceeding 90%.
Related Concept Videos
Symbiosis
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Malaria
Antiprotozoal Agents

