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MR imaging-guided percutaneous cryotherapy for lung tumors: initial experience
Shangang Liu1, Ruimei Ren1, Ming Liu2
1Department of Radiation Oncology, Shandong Cancer Hospital and Institute, School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Science, Jinan, Shandong 250021, China.
Summary
Magnetic resonance (MR) imaging-guided cryotherapy is a feasible and effective minimally invasive treatment for lung tumors. This study shows promising local control and survival rates in patients undergoing this novel procedure.
Area of Science:
- Oncology
- Radiology
- Minimally Invasive Procedures
Background:
- Lung tumors pose a significant health challenge requiring effective treatment options.
- Percutaneous cryotherapy offers a minimally invasive approach to tumor ablation.
- Magnetic resonance (MR) imaging provides real-time guidance for precise treatment delivery.
Purpose of the Study:
- To prospectively evaluate the initial clinical experience and outcomes of MR imaging-guided percutaneous cryotherapy for lung tumors.
- To assess the feasibility, safety, and efficacy of this novel therapeutic approach.
Main Methods:
- MR imaging-guided percutaneous cryotherapy was performed in 21 patients with biopsy-proven lung tumors.
- Follow-up included contrast-enhanced chest computed tomography (CT) scans every 3 months for 12 months or until death to assess tumor control.
- Complications and treatment response were meticulously documented.
Main Results:
- Cryotherapy was successfully completed in all patients, with a 1-year local control rate of 81% and a 1-year survival rate of 90.5%.
- Tumor response at 12 months included complete response in 33.3% and partial response in 47.6% of patients.
- Common complications included pneumothorax (33.3%) and hemoptysis (52.4%), with chest tube placement required in 4.8% of cases.
Conclusions:
- MR imaging-guided percutaneous cryotherapy is a feasible, effective, and minimally invasive treatment option for lung tumors.
- The procedure demonstrates encouraging local tumor control and survival rates.
- Further research is warranted to optimize patient selection and refine the technique.
