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Medication adherence in schizophrenia: a comparison between outpatients and relapse cases
1Discipline of Psychological and Behavioural Medicine, Faculty of Medicine, Universiti Teknologi Mara, Sungai Buloh Campus, 47000 Sungai Buloh, Selangor, Malaysia.
Summary
Medication adherence is poor in schizophrenia patients, with relapse cases showing worse outcomes. Addressing adherence can improve hospital admissions and reduce psychopathology severity.
Area of Science:
- Psychiatry
- Clinical Psychology
- Pharmacology
Background:
- Medication adherence is critical for schizophrenia treatment success.
- Poor adherence leads to severe consequences, including relapse and increased hospitalizations.
- Understanding adherence factors is vital for improving patient outcomes.
Purpose of the Study:
- To compare medication adherence between schizophrenia patients in relapse and those in psychiatric follow-up.
- To identify factors influencing medication adherence in schizophrenia.
Main Methods:
- A cross-sectional study of 70 schizophrenia patients, divided into two equal groups.
- Assessment of medication adherence using the Medication Adherence Rating Scale.
- Measurement of insight, social support, and psychopathology using validated instruments.
Main Results:
- Overall medication adherence was poor, with 51% of patients non-adherent.
- Adherence was numerically better in outpatients (61%) than relapse cases (39%), but not statistically significant.
- Relapse patients exhibited higher rates of admission and severe psychopathology, while outpatients reported better social support.
Conclusions:
- Medication adherence remains a significant challenge for both relapse and outpatient schizophrenia populations.
- Improving medication adherence has the potential to reduce hospital admissions and mitigate psychopathology severity.
- Targeted interventions addressing adherence barriers are crucial for enhancing schizophrenia management.
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